by optimizing the composition ratio and corona poling treatment) coated with poly­

dopamine BaTiO3 nanoparticles showed endogenous electrical potential mimicking of the

bone tissue up to 12 weeks. The resulting osteogenic differentiation gave rise to rapid

bone regeneration and complete mature bone-structure formation [49].

PVDF-graphene oxide (GO) scaffold made by preferential laser sintering technique

showed superior cell behavior with commendable compressive (97.9%) and tensile

strength (24.5%). under the influence of electric field [50]. Ag-decorated barium titanate

(BT) increases the piezoelectric effect of PVDF showed, increased proliferation and dif­

ferentiation of osteosarcoma cells [51]. PVDF nanocomposites owing to their commend­

able electrical conductivity due to electroactive β-phase proved to be good substrates for

direct stem cell differentiation [52]. BaTiO3 incorporated PVDF/MWNT matrixes induce

electro-physiologically distinguishable glial-like differentiation and neurogenesis of

neural stem cells (Figure 23.7iii) [52] (Table 23.1).

23.5 Conclusion and Future Aspects

Further, understanding the CP-based flexible bioelectronics interaction with electro re­

sponsive tissue in vivo need to be explored to understand and analyze the retention of

FIGURE 23.6

Representation of established application with various use of well-explored PEDOT in flexible electronics and novel

challenges which could enhance the property to utilize the polymer to its fullest [ 46]. Copyright (2019) Advanced

Science. The article was printed under a CC-BY license ( http://creativecommons.org/licenses/by/4.0/).

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